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research Functional Genomics Comparative Genomics QTL Mapping Livestock Genome Sequencing Initiative

Denis M.Larkin


Educational Background
Ph.D. in Genetics, Institute of Cytology and Genetics, Russia, 2000.
M.S. in Biology, Novosibirsk State University, Russia, 1997.
B.S. in Biology, Novosibirsk State University, Russia, 1995.

Current Projects
Multispecies Genome Analysis; Fine Mapping of Economic Trait Loci and Determinantion of their Allele Frequency; Resequencing of QTL Regions; SNP Discovery

Areas of interest
Comparative Mammalian Genomics, Chromosome Analysis, and Evolution

Selected Publications

Comparative mapping of cattle chromosome 19: cytogenetic localization of 19 BAC clones. Larkin, D.M., N.M. Astakhova, M.A. Prokhorovich, H.A. Lewin and N.S. Zhdanova. 2006. Cytogenetics and Genome Research 112:235-240.

Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Murphy W.J., D.M. Larkin, A. Everts-van der Wind, G. Bourque, G. Tesler, L. Auvil, J.E. Beever, B.P. Chowdhary, F. Galibert, L. Gatzke, C. Hitte, S.N. Meyers, D. Milan, E.A. Ostrander, G. Pape, H.G. Parker, T. Raudsepp, M.B. Rogatcheva, L.B. Schook, L.C. Skow, M. Welge, J.E. Womack, S.J. O'Brien, P.A. Pevzner, and H.A. Lewin. 2005. Science 309:613-617.

Identification of a missense mutation in the bovine ABCG2 gene with major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle. Cohen-Zinder M., E. Seroussi, D.M. Larkin, J.J. Loor, A. Everts-van der Wind, J.H. Lee, J.K. Drackley, M.R. Band, A.G. Hernandez, M. Shani, H.A. Lewin, J.I. Weller and M. Ron. 2005. Genome Research 15:936-944.

A cattle-human comparative map built with cattle BAC-ends and human genome sequence. Larkin D.M., A. Everts-van der Wind, M. Rebeiz, P.A. Schweitzer, S. Bachman, C.A. Green, C.L. Wright, E.J. Campos, L.D. Benson, J. Edwards, L. Liu, K. Osoegawa, J.E. Womack, P.E. de Jong and H.A. Lewin 2003. Genome Research, 13:1966-1972.

  Laboratory of Mammalian Genome Biology
University of Illinois at Urbana-Champaign
206 Edward R. Madigan Laboratory 
1201 West Gregory Drive 
Urbana, IL 61801

Phone 217-244-6745